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试剂存储系统作为测序仪的核心模块,为测序试剂提供稳定的低温冷藏环境。该系统主要由取样运动机构、试剂存储仓及温控系统3部分构成,温控系统采用半导体制冷片(TEC)与风冷相结合的设计方案,兼顾制冷效率与运行稳定性和结构小型化,使试剂存储仓满足测序试剂(6±2)℃的冷藏温度要求。测试结果表明,本工作设计的温控系统可稳定实现(4±0.5)℃的温控精度要求,试剂存储仓满足测序试剂(6±2)℃冷藏温度要求。综上,该试剂存储系统设计方案符合行业相关设计规范,可为后续基因测序仪试剂存储系统的优化设计与开发提供参考,对推动测序仪的国产化进程,提升核心技术自主可控具有重要意义。
Abstract:As a core module of the gene sequencer, the reagent storage system provides a stable low-temperature refrigeration environment for sequencing reagents. The system mainly consists of three parts: sampling mechanism, reagent storage chamber, and temperature control system. The temperature control system adopts a design combining a thermoelectric cooler(TEC) and air cooling, balancing cooling efficiency, operational stability, and structural miniaturization, enabling the reagent storage chamber to meet the refrigeration temperature requirements of sequencing reagents at(6±2) ℃. Test results demonstrate that the temperature control system reliably achieves a temperature control accuracy of(4±0.5) ℃, and the reagent storage chamber meets the requirement of refrigeration temperature at(6±2) ℃ for sequencing reagents. In summary, the proposed design of the reagent storage system complies with relevant industry specifications, provides a valuable reference for subsequent optimization and development of reagent storage systems for gene sequencers. It is of significant importance in promoting the localization process of the sequencing instruments and enhancing the independent controllability of its core technologies.
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基本信息:
中图分类号:TH79
引用信息:
[1]伍江,卢亭亭,曹雪.基因测序仪试剂存储系统设计及温控测试研究[J].分析仪器,2026,No.267(04):8-12.
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